The application of colloidal gold technology in the diagnosis of parasitic disea

Most parasitic diseases are zoonotic, therefore, the diagnosis of parasitic diseases in livestock and poultry is of great public health significance. Li Xuewu et al. developed a gold standard test strip for trichinosis using recombinant secreted antigens of Trichinella spiralis, which has good specificity and sensitivity, and is consistent with the results of ELISA and digestion methods. The colloidal gold test strip diagnostic method established by He Wei et al. for detecting schistosome antibodies has high sensitivity and strong specificity, with negative coincidence rates of~95.3%. Malaria is a serious insect borne infectious disease that poses a serious threat to human health, with the pathogen being Plasmodium. Developing a simple, sensitive and suitable diagnostic kit for grassroots applications is an urgent issue that needs to be addressed in malaria prevention and control. In recent years, the sensitivity of monoclonal antibody based immunoassay (ICT) in the diagnosis of malaria has demonstrated its broad application prospects. In addition, the detection of antibodies against other parasites such as Schistosoma japonicum, Schistosomiasis, Fasciosomiasis in cows, Schistosomiasis in sheep, Schistosomiasis in sheep, Echinococcus granulosus, etc., especially colloidal gold test strips for protozoa, are currently being developed, and some are also undergoing clinical trials